Venice is divided into six districts called sestieri with own municipal administration and house numbering system, unique for each sestiere and quite confusing for tourists and guests of the city. Venice is such a tiny place that getting from A to B is never a problem regardless of where A and B are, given of course that you mastered the art of navigating Venetian canals and bridges (or lack thereof). Any rental apartment you choose in the old city has a central location by definition, regardless of what district of Venice it is in.
Cannaregio is located on the northwestern part of Venice and is the most populated district of the city with 20 000 people living there. Its points of interest include the museum of CaвЂ™dвЂ™Oro, the Venetian Ghetto and the Gullie bridge.
San-Polo is the smallest and the oldest part of town occupying only around 85 acres of venetian land. It is named after the church of San-Polo. The other attractions are the church of Santa Maria Gloriosa dei Frari, the Rialto bridge, Scuola Grande di San Rocco and others.
San-Marco is as central as it gets in Venice, because the main basilica of the city вЂ“ Basilica di San Marco, of course вЂ“ is located here. It is the most touristy area of Venice where once the Venetian government was housed.
Dorsoduro (along with the island of Guidecca) is on the southern side of Venice and the land most elevated above the sea level which is no small feat in the city where tides and floods are so common. In part residential, in part arty, it attracts tourists because of the galleries of Accademia that are located here.
Castello is the largest district of Venice, whose attractions include the Biennale Gardens, Scuola Grande di San Marco and the church of Santi Giovanni e Paolo.
A large chunk of Santa Croce district used to be the Luprio swamp, which in the 20th century was drained and built on extensively. This is where Piazzale Roma, the cityвЂ™s transportation hub and the largest parking lot, can be found. You canвЂ™t take your car any further.